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III. SPECIFIC BLEEDING DISORDERS IN LIVER DISEASE (cont'd)

Moderators: W Lee/T Lisman
Hyperfibrinolysis
B. Gail Macik, MD (UVA)
Platelet dysfunction
Don A. Gabriel, MD, PhD (UNC)

IV. DEALING WITH LIVER DISEASE COAGULOPATHY IN SPECIFIC CLINICAL SITUATIONS: WHAT IS THE EVIDENCE AND WHAT ARE THE ISSUES?
Moderators: C Berg/T Pruett/A Tripodi
Variceal bleeding
Arun J. Sanyal, MD (VCU)
Paracentesis/Thoracentesis
Patrick G. Northup, MD (UVA)
GAVE and portal gastropathy
Abdullah Al-Osaimi, MBBS (UVA)
Liver biopsy
Stephen H. Caldwell, MD (UVA)
Central lines
David L. Bogdonoff, MD (UVA)
Endoscopy/polypectomy/ERCP
Kris V. Kowdley, MD, FACP (University of Washington)
Oral surgery
Andrew Martoff, DDS (UVA)
General and special surgery in the liver disease patient
Reid B. Adams, MD (UVA)
Intracranial pressure monitors
Thomas P. Bleck, MD (UVA)
Liver transplantation and coagulopathy
Timothy Pruett, MD (UVA)

V. ISSUES IN MANAGEMENT:   WHAT ARE THE INDICATIONS?  WHAT ARE THE OPTIONS? WHAT ARE THE LIMITATIONS?
WHAT ARE THE OBLIGATIONS?

Moderators: BG Macik/A Al-Osaimi/P Grant
Therapy: Available agents
Don A. Gabriel, MD, PhD (UNC)
Risk-benefit of different agents
J.A. Lisman, PhD (UMC Utrecht)
Prophylactic or rescue therapy
Carl L. Berg, MD (UVA)
Legal Considerations
Jeffrey O’Connell (UVA Law)

VI. HYPERCOAGULATION IN LIVER DISEASE
Moderators: PG Northup/MR Hoffman
Hypercoagulation in liver disease
B. Gail Macik, MD (UVA)
Hypercoagulation in NASH and Metabolic Syndrome
Peter Grant, MD (University of Leeds)
Portopulmonary Syndrome
Michael B. Fallon, MD (University of Alabama)
Parenchymal extinction
Ian R. Wanless, MD (University of Toronto)
CVVD/HD/Artificial liver support: effects of procoagulants
Rasheed A. Balogun, MBBS (UVA)
Portal vein thrombosis
K. Rajender Reddy, MD (U Penn)
Defibrotide in VOD: anti-coagulant and more?
Arsinur B. Oral, MD (UVA)
Closing: Summary and future directions
AJ Sanyal/SH Caldwell

CLOSING SUMMARY AND FUTURE DIRECTIONS
A.J. Sanyal/S.H. Caldwell


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